![]() ![]() However, precisely because of its good efficacy and safety, ibuprofen is being increasingly used in paediatric care, even without medical prescription. In recent years, various reviews and meta-analyses have confirmed the good efficacy and tolerability profile of ibuprofen, especially when compared to other NSAIDs. Since its marketing as an oral suspension for paediatric use, ibuprofen has replaced acetylsalicylic acid for the treatment of inflammation, avoiding the risk of Reye’s syndrome. Ibuprofen is the most widely used non-steroidal anti-inflammatory drug (NSAID) for the treatment of inflammation, mild-to-moderate pain and fever in children and, thanks to its good tolerability profile, the only NSAID approved for use in children over 3 months old. Ibuprofen remains the drug of first choice in the treatment of inflammatory pain in children. Ibuprofen should not be used as an antipyretic, except in rare cases. Most of the analysed studies reported adverse events when ibuprofen was being used for fever symptoms or flu-like syndrome. It is contraindicated in neonates and in children with wheezing and persistent asthma and/or during varicella. ![]() Likewise, ibuprofen should never be administered to patients who are sensitive to it or to other NSAIDs. Dehydration plays an important role in triggering renal damage, so ibuprofen should not be given to patients with diarrhoea and vomiting, with or without fever. The literature from 2000 to date demonstrates that gastrointestinal events are rare, but (when they occur) include both upper and lower digestive tract lesions. The purpose of this work was a critical review of the paediatric literature over the last 15 years on side effects and adverse events associated with ibuprofen, in order to highlight circumstances associated with higher risks and to promote safe and appropriate use of this drug. However, an increase of suspected adverse reactions to ibuprofen has been noted in concomitance with the raised, often medically unsupervised, consumption of the drug. Its efficacy and safety profile have led to its increasing use in paediatric care, even without medical prescription. ![]() Ibuprofen is the most widely used non-steroidal anti-inflammatory drug (NSAID) for the treatment of inflammation, mild-to-moderate pain and fever in children, and is the only NSAID approved for use in children aged ≥3 months. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |